When drying film, I use the minimum wetting agent, hang it, turn off the heater, the light, and the fan, and leave it alone.
When I am loading sheet film holders I make sure to vacuum them out, and wipe down the bench with a 'tacky' micropore cloth.
Periodically I vacuum the whole room with a HEPA grade machine, and I am not above using an air cleaner for a few hours.
It is generally not too dry here - in fact my darkroom tends to have a higher humidity than the outside - and that helps keep dust down. I also only use the darkroom for darkroom work which keeps unavoidable human shedding to a minimum.
I make sure to wipe down surfaces after I have been weighing chemicals, and to wipe up drips outside the sink.
All this is not perfect, but I rarely have to do a lot of spotting.